{"id":2439,"date":"2018-09-07T17:30:29","date_gmt":"2018-09-07T08:30:29","guid":{"rendered":"https:\/\/www.saisei-mirai.or.jp\/ssf\/?p=2439"},"modified":"2025-05-09T13:21:01","modified_gmt":"2025-05-09T04:21:01","slug":"macrophage_eng","status":"publish","type":"post","link":"https:\/\/saisei-mirai.or.jp\/en\/macrophage_eng\/","title":{"rendered":"GcMAF (Gc Protein derived  Macrophage Activating Factor)"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"2439\" class=\"elementor elementor-2439\">\n\t\t\t\t\t\t<div class=\"elementor-inner\">\n\t\t\t\t<div class=\"elementor-section-wrap\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-330aa47 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"330aa47\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-71855c7\" data-id=\"71855c7\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-41be34a elementor-widget elementor-widget-spacer\" data-id=\"41be34a\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-43ab2d0 elementor-widget elementor-widget-text-editor\" data-id=\"43ab2d0\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<h2 id=\"id01\">New GcMAF<\/h2><p class=\"\" data-start=\"134\" data-end=\"542\">NEW GcMAF is produced using a patented process developed in Japan by Saisei Mirai, in collaboration with researchers from the University of Tokushima, who have been conducting GcMAF research for over 20 years. Manufactured in our sterile cell processing facility, this advanced formulation is 10\u201315 times more concentrated than conventional GcMAF and offers significantly enhanced stability and bioactivity.<\/p><p class=\"\" data-start=\"544\" data-end=\"953\">Clinically, this higher-concentration GcMAF has demonstrated a favorable safety profile, with the vast majority of patients experiencing no adverse effects. In rare cases (approximately 1 in 100), mild and transient symptoms such as low-grade fever or eczema may occur. Its improved resistance to oxidation contributes to greater stability, making NEW GcMAF a reliable and effective option for immune support.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8b0e72e elementor-widget elementor-widget-text-editor\" data-id=\"8b0e72e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<h3>First-Generation GcMAF vs. Saisei Mirai NEW GcMAF (formerly 2nd Generation)<\/h3>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d3ed512 elementor-widget elementor-widget-image\" data-id=\"d3ed512\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"497\" height=\"403\" src=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/macrophage_graph_saisei_mirai_second_generation_gcmaf_concentration.png\" class=\"attachment-large size-large wp-image-5612\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/macrophage_graph_saisei_mirai_second_generation_gcmaf_concentration.png 497w, https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/macrophage_graph_saisei_mirai_second_generation_gcmaf_concentration-300x243.png 300w\" sizes=\"(max-width: 497px) 100vw, 497px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7cb7910 elementor-widget elementor-widget-text-editor\" data-id=\"7cb7910\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<p class=\"\" data-start=\"141\" data-end=\"212\">\u00a0<\/p><p class=\"\" data-start=\"93\" data-end=\"139\"><strong data-start=\"93\" data-end=\"139\">New GcMAF \u2013 Concentration and Clinical Use<\/strong><\/p><p class=\"\" data-start=\"141\" data-end=\"212\">Each 0.5 mL vial of New GcMAF contains approximately 1,500 ng of GcMAF.<\/p><p class=\"\" data-start=\"214\" data-end=\"446\">GcMAF is a naturally derived immunotherapy product. As with other immune components such as lymphocytes and natural killer (NK) cells, the concentration of GcMAF may vary slightly due to individual differences in serum composition.<\/p><p class=\"\" data-start=\"448\" data-end=\"628\">At Saisei Mirai, New GcMAF is produced under strict aseptic conditions in a certified cell processing facility. All products undergo sterile filtration to ensure safety and purity.<\/p><p class=\"\" data-start=\"630\" data-end=\"896\">Since April 2011, New GcMAF (formerly known as 2nd Generation GcMAF) has been safely administered to hundreds of patients in our clinics across Japan. Clinical application methods have included intramuscular (IM), subcutaneous (SC), and intratumoral (IT) injections.<\/p><p>\u00a0<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-012845b elementor-widget elementor-widget-spacer\" data-id=\"012845b\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3791b7e elementor-widget elementor-widget-text-editor\" data-id=\"3791b7e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<h3><span style=\"text-decoration: underline\">Our specialized sterile Cell Processing Center (CPC) and team of highly skilled laboratory staff<\/span><\/h3>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-183285f3 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"183285f3\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-69a6fb09\" data-id=\"69a6fb09\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3a8a2536 elementor-widget elementor-widget-image\" data-id=\"3a8a2536\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"500\" src=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/CPC_ent_8x5.jpg\" class=\"attachment-large size-large wp-image-2387\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/CPC_ent_8x5.jpg 800w, https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/CPC_ent_8x5-300x188.jpg 300w, https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/CPC_ent_8x5-768x480.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">Clean room<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-26a8d7fd\" data-id=\"26a8d7fd\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-38295789 elementor-widget elementor-widget-image\" data-id=\"38295789\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"500\" src=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/OS-02.jpg\" class=\"attachment-large size-large wp-image-5160\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/OS-02.jpg 800w, https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/OS-02-300x188.jpg 300w, https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/OS-02-768x480.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">Clean clothes<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-2f03f423\" data-id=\"2f03f423\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-70aed43d elementor-widget elementor-widget-image\" data-id=\"70aed43d\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"500\" src=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/OS-03.jpg\" class=\"attachment-large size-large wp-image-5161\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/OS-03.jpg 800w, https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/OS-03-300x188.jpg 300w, https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/OS-03-768x480.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">Microscope work<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-47951753 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"47951753\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-15cbd302\" data-id=\"15cbd302\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2aa24b1 elementor-widget elementor-widget-image\" data-id=\"2aa24b1\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"500\" src=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/OS-04.jpg\" class=\"attachment-large size-large wp-image-5162\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/OS-04.jpg 800w, https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/OS-04-300x188.jpg 300w, https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/OS-04-768x480.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">Carbon dioxide incubator<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-66189909\" data-id=\"66189909\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-311b40ef elementor-widget elementor-widget-image\" data-id=\"311b40ef\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"500\" src=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/OS-05.jpg\" class=\"attachment-large size-large wp-image-5163\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/OS-05.jpg 800w, https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/OS-05-300x188.jpg 300w, https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/OS-05-768x480.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\"> Centrifuge <\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-2c1d13f9\" data-id=\"2c1d13f9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7fe280bc elementor-widget elementor-widget-image\" data-id=\"7fe280bc\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"500\" src=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/OS-06.jpg\" class=\"attachment-large size-large wp-image-5164\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/OS-06.jpg 800w, https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/OS-06-300x188.jpg 300w, https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/OS-06-768x480.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">Sterile cabinet<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3c5f81f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3c5f81f\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-be24da7\" data-id=\"be24da7\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-01dcb22 elementor-widget elementor-widget-spacer\" data-id=\"01dcb22\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7a29f1f elementor-widget elementor-widget-text-editor\" data-id=\"7a29f1f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<p class=\"\" data-start=\"177\" data-end=\"218\"><strong data-start=\"177\" data-end=\"218\">How is Saisei Mirai\u2019s New GcMAF Made?<\/strong><\/p><p class=\"\" data-start=\"220\" data-end=\"531\">Saisei Mirai\u2019s New GcMAF is produced in our own sterile, certified Cell Processing Center (CPC) in Japan. It is derived from the serum of carefully screened, healthy donors. Every step of the manufacturing process follows strict quality and safety standards to ensure a high-purity, clinically reliable product.<\/p><p class=\"\" data-start=\"533\" data-end=\"789\">The serum is processed using our patented method, and the final product is sterile filtered to remove any potential contaminants. Comprehensive testing is conducted at each stage to ensure the safety, stability, and consistency of the final GcMAF solution.<\/p><blockquote data-start=\"791\" data-end=\"856\"><p class=\"\" data-start=\"793\" data-end=\"856\">See <strong data-start=\"797\" data-end=\"819\">Tests of our GcMAF<\/strong> below for more detailed information.<\/p><\/blockquote>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-748a015 elementor-widget elementor-widget-image\" data-id=\"748a015\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"896\" height=\"293\" src=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/macrophage_gcmaf_preparation-1024x335.gif\" class=\"attachment-large size-large wp-image-5627\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/macrophage_gcmaf_preparation-1024x335.gif 1024w, https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/macrophage_gcmaf_preparation-300x98.gif 300w, https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/macrophage_gcmaf_preparation-768x251.gif 768w, https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/macrophage_gcmaf_preparation-1200x392.gif 1200w\" sizes=\"(max-width: 896px) 100vw, 896px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c82139f elementor-widget elementor-widget-spacer\" data-id=\"c82139f\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-71a90fd elementor-widget elementor-widget-text-editor\" data-id=\"71a90fd\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<p class=\"\" data-start=\"178\" data-end=\"245\"><strong data-start=\"178\" data-end=\"245\">How is Saisei Mirai\u2019s New GcMAF Tested for Biological Activity?<\/strong><\/p><p class=\"\" data-start=\"247\" data-end=\"527\">Saisei Mirai\u2019s New GcMAF is evaluated for macrophage-activating activity through a validated phagocytosis assay conducted at the University of Tokushima. In this test, mouse macrophages are exposed to opsonized sheep red blood cells\u2014marked for ingestion by activated immune cells.<\/p><p class=\"\" data-start=\"529\" data-end=\"842\">The degree of macrophage activation is assessed by measuring the number of red blood cells ingested by each macrophage, visualized as purple inclusions within otherwise clear cells. From these results, the <strong data-start=\"735\" data-end=\"762\">Phagocytosis Index (PI)<\/strong> is calculated, providing a quantitative measure of GcMAF\u2019s biological activity.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-091b658 elementor-widget elementor-widget-image\" data-id=\"091b658\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"500\" height=\"375\" src=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/macrophage_gcmaf_phagocytic_activity_tokushima01_sml.jpg\" class=\"attachment-large size-large wp-image-5629\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/macrophage_gcmaf_phagocytic_activity_tokushima01_sml.jpg 500w, https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/macrophage_gcmaf_phagocytic_activity_tokushima01_sml-300x225.jpg 300w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-21060aa elementor-widget elementor-widget-text-editor\" data-id=\"21060aa\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<p class=\"\" data-start=\"123\" data-end=\"429\"><strong data-start=\"123\" data-end=\"178\">Macrophage Phagocytic Activity Induced by New GcMAF<\/strong><br data-start=\"178\" data-end=\"181\" \/>This image shows macrophages activated by New GcMAF, actively phagocytizing opsonized red blood cells. The ingested red blood cells appear as clear structures within the purple-stained macrophages.<br data-start=\"378\" data-end=\"381\" \/><em data-start=\"381\" data-end=\"429\">Photo courtesy of the University of Tokushima.<\/em><\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7351176 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"7351176\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-8f7a294\" data-id=\"8f7a294\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b66106c elementor-widget elementor-widget-spacer\" data-id=\"b66106c\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4406330 elementor-widget elementor-widget-text-editor\" data-id=\"4406330\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<p class=\"\" data-start=\"108\" data-end=\"133\"><strong data-start=\"108\" data-end=\"133\">What Are Macrophages?<\/strong><\/p><p class=\"\" data-start=\"135\" data-end=\"387\">Macrophages\u2014literally meaning \u201cbig eaters\u201d in Greek\u2014are specialized immune cells derived from monocytes, a type of white blood cell. Found throughout body tissues, they play a central role in both innate (non-specific) and adaptive (specific) immunity.<\/p><p class=\"\" data-start=\"389\" data-end=\"698\">Their primary function is <strong data-start=\"415\" data-end=\"431\">phagocytosis<\/strong>\u2014the process of engulfing and digesting pathogens, cancer cells, and cellular debris. Macrophages can act as stationary sentinels or move throughout the body, and they also help activate other immune cells, such as lymphocytes, to mount a coordinated immune response.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-40fbe82 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"40fbe82\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-77e61ce\" data-id=\"77e61ce\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-806be1e elementor-widget elementor-widget-image\" data-id=\"806be1e\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"400\" height=\"288\" src=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/macrophage03.gif\" class=\"attachment-large size-large wp-image-2453\" alt=\"\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-afedea1\" data-id=\"afedea1\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d74c4b5 elementor-widget elementor-widget-text-editor\" data-id=\"d74c4b5\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<h4><span style=\"color: #ff6600\"><strong>Steps of a macrophage ingesting a pathogen<\/strong><\/span><\/h4><p><strong><span style=\"color: #ff0000\">a<\/span>.<\/strong> Ingestion through phagocytosis, a phagosome is formed<br \/><strong><span style=\"color: #ff0000\">b<\/span>.<\/strong> The fusion of lysosomes with the phagosome creates a phagolysosome; the pathogen is broken down by enzymes<br \/><strong><span style=\"color: #ff0000\">c<\/span>.<\/strong> Waste material is expelled or assimilated (the latter not pictured)<\/p><p><strong>Parts:<\/strong> <span style=\"color: #ff0000\">1<\/span>. Pathogens, <span style=\"color: #ff0000\">2<\/span>. Phagosome, <span style=\"color: #ff0000\">3<\/span>. Lysosomes, <span style=\"color: #ff0000\">4<\/span>. Waste material, <span style=\"color: #ff0000\">5<\/span>. Cytoplasm, <span style=\"color: #ff0000\">6<\/span>. Cell membrane<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4534d13 elementor-widget elementor-widget-html\" data-id=\"4534d13\" data-element_type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<a href=\"https:\/\/ja.wikipedia.org\/wiki\/%E3%83%9E%E3%82%AF%E3%83%AD%E3%83%95%E3%82%A1%E3%83%BC%E3%82%B8\" target=\"_blank\">Image source: Wikipedia<\/a>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c51f785 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c51f785\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-b04af0b\" data-id=\"b04af0b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2512b87 elementor-widget elementor-widget-spacer\" data-id=\"2512b87\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-49b4c68 elementor-widget elementor-widget-text-editor\" data-id=\"49b4c68\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<p class=\"\" data-start=\"161\" data-end=\"203\"><strong data-start=\"161\" data-end=\"203\">Vitamin D Binding Protein (Gc Protein)<\/strong><\/p><p class=\"\" data-start=\"205\" data-end=\"551\">Vitamin D binding protein (DBP), also known as <strong data-start=\"252\" data-end=\"266\">Gc Protein<\/strong>, is a multifunctional plasma protein primarily produced in the liver, particularly in response to sunlight exposure. Its main role is to bind and transport 25-hydroxyvitamin D [25(OH)D], the circulating form of vitamin D, facilitating its storage and distribution throughout the body.<\/p><p class=\"\" data-start=\"553\" data-end=\"991\">Among the different forms of DBP, the most prevalent is a non-glycosylated 656 Da protein. In addition to its role in vitamin D metabolism, DBP serves as a critical <strong data-start=\"718\" data-end=\"756\">scavenger of extracellular G-actin<\/strong>, especially relevant in liver injury and disease. Furthermore, through specific glycosylation (GalNAc-modification), Gc Protein can be converted into a <strong data-start=\"909\" data-end=\"947\">macrophage activating factor (MAF)<\/strong>, which plays a key role in immune function.<\/p><p class=\"\" data-start=\"993\" data-end=\"1274\">Notably, vitamin D binding protein has minimal influence on vitamin D&#8217;s biological activity or distribution in the body, meaning elevated DBP levels generally do not pose health concerns. It is considered the <strong data-start=\"1202\" data-end=\"1255\">primary precursor of macrophage activating factor<\/strong> in the human body.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-60cf587 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"60cf587\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-60b4cef\" data-id=\"60b4cef\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9a3ffb5 elementor-widget elementor-widget-spacer\" data-id=\"9a3ffb5\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-49e013e elementor-widget elementor-widget-text-editor\" data-id=\"49e013e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<p class=\"\" data-start=\"123\" data-end=\"205\"><strong data-start=\"123\" data-end=\"161\">Macrophage Activation Factor (MAF)<\/strong><br data-start=\"161\" data-end=\"164\" \/><strong data-start=\"164\" data-end=\"205\">What is Macrophage Activation Factor?<\/strong><\/p><p class=\"\" data-start=\"207\" data-end=\"622\">Macrophage Activation Factor (MAF) refers to a group of glycoproteins that enhance the activity of macrophages, key immune cells involved in the detection and destruction of pathogens, abnormal cells, and cellular debris. MAF stimulates macrophages to become more active in immune defense, but it does <strong data-start=\"509\" data-end=\"516\">not<\/strong> convert them into natural killer (NK) cells\u2014these are separate immune cell types with distinct functions.<\/p><p class=\"\" data-start=\"624\" data-end=\"962\">The primary precursor to MAF in the human body is <strong data-start=\"674\" data-end=\"709\">Vitamin D Binding Protein (DBP)<\/strong>, also known as <strong data-start=\"725\" data-end=\"739\">Gc Protein<\/strong>. When Gc Protein undergoes specific glycosylation, particularly GalNAc modification, it becomes an active form of MAF. This glycosylated Gc Protein is considered one of the most effective natural activators of macrophages.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e5f3126 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e5f3126\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a1e0f94\" data-id=\"a1e0f94\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9dfe75b elementor-widget elementor-widget-spacer\" data-id=\"9dfe75b\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8a59119 elementor-widget elementor-widget-menu-anchor\" data-id=\"8a59119\" data-element_type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div id=\"Taisyou\" class=\"elementor-menu-anchor\"><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6878109 elementor-widget elementor-widget-text-editor\" data-id=\"6878109\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<h3><span style=\"text-decoration: underline\">NaGaLase (Alpha-N-acetylgalactosaminidase)<\/span><\/h3><p>NaGaLase is an enzyme produced in trace amounts in normal healthy liver cells.<\/p><h4><span style=\"text-decoration: underline\">What harm can NaGaLase do?<\/span><\/h4><p>Alpha-N-acetylgalactosaminidase (alpha-NaGaLase) is produced in large amounts by cancer cells. alpha-NaGaLase deglycosylates the trisaccharide of Gc\u00a0Protein at step prior to the final isoform of MAF. alpha-NaGaLase from tumors induces an immunosuppressive state that allows the cancer to spread and eventually results in death by infection.<\/p><h5><span style=\"text-decoration: underline\">What good can NaGaLase do?<\/span><\/h5><p>Endo-alpha-N-acetylgalactosaminidase is produced in small amounts by probiotic bifodobacterium. NaGaLase produced in the intestine by our probiotics serves a role in breaking down mucin glycoproteins in our food.<\/p><h5><span style=\"text-decoration: underline\">Where else is NaGaLase found?<\/span><\/h5><p>NaGaLase is also produced by bacteria, virus infected cells and fungi.<\/p><h5><span style=\"text-decoration: underline\">Normal serum levels of NaGaLase<\/span><\/h5><p>Normal levels of NaGaLase range between 0.38 to 0.63\u00a0nmole\/min\/mg protein. People with cancer have NaGaLase above 2.32\u00a0nmole\/min\/mg protein.<\/p><p>Radiation therapy decreases the number of cancerous cells capable of secreting alpha-NaGaLase. Radiation also increases Gc\u00a0Protein activation to principle MAF. Radiotherapy and photodynamic therapy decreases NaGaLase activity.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b3f813d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b3f813d\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-afd389b\" data-id=\"afd389b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-79935b1 elementor-widget elementor-widget-spacer\" data-id=\"79935b1\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d9cd8fd elementor-widget elementor-widget-text-editor\" data-id=\"d9cd8fd\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<p class=\"\" data-start=\"162\" data-end=\"205\"><strong data-start=\"162\" data-end=\"205\">Target Conditions for New GcMAF Therapy<\/strong><\/p><p class=\"\" data-start=\"207\" data-end=\"386\">New GcMAF (Macrophage Activating Factor) therapy supports immune function and has been used as a complementary approach in the management of a wide range of conditions, including:<\/p><ul data-start=\"388\" data-end=\"818\"><li class=\"\" data-start=\"388\" data-end=\"398\"><p class=\"\" data-start=\"390\" data-end=\"398\">Cancer<\/p><\/li><li class=\"\" data-start=\"399\" data-end=\"477\"><p class=\"\" data-start=\"401\" data-end=\"477\">Infectious diseases (including antibiotic-resistant bacteria and COVID-19)<\/p><\/li><li class=\"\" data-start=\"478\" data-end=\"512\"><p class=\"\" data-start=\"480\" data-end=\"512\">Autism spectrum disorder (ASD)<\/p><\/li><li class=\"\" data-start=\"513\" data-end=\"550\"><p class=\"\" data-start=\"515\" data-end=\"550\">Chronic fatigue syndrome (CFS\/ME)<\/p><\/li><li class=\"\" data-start=\"551\" data-end=\"572\"><p class=\"\" data-start=\"553\" data-end=\"572\">Atopic dermatitis<\/p><\/li><li class=\"\" data-start=\"573\" data-end=\"597\"><p class=\"\" data-start=\"575\" data-end=\"597\">Hair loss (alopecia)<\/p><\/li><li class=\"\" data-start=\"598\" data-end=\"620\"><p class=\"\" data-start=\"600\" data-end=\"620\">Multiple sclerosis<\/p><\/li><li class=\"\" data-start=\"621\" data-end=\"664\"><p class=\"\" data-start=\"623\" data-end=\"664\">Pollinosis (seasonal allergic rhinitis)<\/p><\/li><li class=\"\" data-start=\"665\" data-end=\"688\"><p class=\"\" data-start=\"667\" data-end=\"688\">Autoimmune diseases<\/p><\/li><li class=\"\" data-start=\"689\" data-end=\"716\"><p class=\"\" data-start=\"691\" data-end=\"716\">Injury recovery support<\/p><\/li><li class=\"\" data-start=\"717\" data-end=\"729\"><p class=\"\" data-start=\"719\" data-end=\"729\">Epilepsy<\/p><\/li><li class=\"\" data-start=\"730\" data-end=\"760\"><p class=\"\" data-start=\"732\" data-end=\"760\">Neurodegenerative diseases<\/p><\/li><li class=\"\" data-start=\"761\" data-end=\"818\"><p class=\"\" data-start=\"763\" data-end=\"818\">For rejuvenation and healthy longevity<\/p><\/li><\/ul><p class=\"\" data-start=\"820\" data-end=\"1055\">In individuals with a well-functioning immune system, the body may be able to naturally fight many diseases. However, those with weakened or compromised immune responses may benefit significantly from immune modulation using New GcMAF.<\/p><p class=\"\" data-start=\"1057\" data-end=\"1315\"><strong data-start=\"1057\" data-end=\"1086\">Safety and Administration<\/strong><br data-start=\"1086\" data-end=\"1089\" \/>Since 2011, New GcMAF has been safely administered in our clinics in Japan to hundreds of patients. The therapy is delivered by intramuscular (IM), subcutaneous (SC), or intratumoral (IT) injection, depending on the condition.<\/p><p class=\"\" data-start=\"1317\" data-end=\"1483\">Adverse effects are rare and typically mild. Approximately 1 in 100 patients may experience a low-grade fever or temporary eczema, both of which resolve on their own.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e91d139 elementor-widget elementor-widget-text-editor\" data-id=\"e91d139\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<h3 data-start=\"196\" data-end=\"240\"><span style=\"text-decoration: underline\"><strong data-start=\"196\" data-end=\"240\">Combining New GcMAF with Other Therapies<\/strong><\/span><\/h3><p class=\"\" data-start=\"242\" data-end=\"481\">New GcMAF can be safely integrated with a wide range of conventional and advanced therapies. This <strong data-start=\"340\" data-end=\"364\">integrative medicine<\/strong> approach is designed to enhance overall therapeutic effectiveness while supporting and modulating the immune system.<\/p><h3 class=\"\" data-start=\"483\" data-end=\"534\">Compatibility with Standard Cancer Treatments<\/h3><p class=\"\" data-start=\"535\" data-end=\"607\">New GcMAF may be used alongside anti-cancer drugs and radiation therapy:<\/p><ul data-start=\"609\" data-end=\"902\"><li class=\"\" data-start=\"609\" data-end=\"757\"><p class=\"\" data-start=\"611\" data-end=\"757\"><strong data-start=\"611\" data-end=\"627\">Chemotherapy<\/strong>: For best results, administer GcMAF a few days apart from chemotherapy to avoid potential suppression of macrophage activation.<\/p><\/li><li class=\"\" data-start=\"758\" data-end=\"902\"><p class=\"\" data-start=\"760\" data-end=\"902\"><strong data-start=\"760\" data-end=\"781\">Radiation therapy<\/strong>: Can be used concurrently with GcMAF, as radiation does not significantly interfere with its immune-stimulating effects.<\/p><\/li><\/ul><p class=\"\" data-start=\"904\" data-end=\"1122\">In our clinical experience, combining GcMAF with <strong data-start=\"953\" data-end=\"980\">palliative radiotherapy<\/strong> has produced promising tumor-reducing effects, especially in patients with prior chemotherapy. See our <strong data-start=\"1084\" data-end=\"1100\">Case Reports<\/strong> for more information.<\/p><h3 class=\"\" data-start=\"1124\" data-end=\"1163\">Integrative Combination Therapies<\/h3><p class=\"\" data-start=\"1164\" data-end=\"1280\">New GcMAF may also be used in combination with a wide range of supportive and immunomodulatory therapies, including:<\/p><ul data-start=\"1282\" data-end=\"1771\"><li class=\"\" data-start=\"1282\" data-end=\"1315\"><p class=\"\" data-start=\"1284\" data-end=\"1315\"><strong data-start=\"1284\" data-end=\"1313\">Sonodynamic Therapy (SDT)<\/strong><\/p><\/li><li class=\"\" data-start=\"1316\" data-end=\"1350\"><p class=\"\" data-start=\"1318\" data-end=\"1350\"><strong data-start=\"1318\" data-end=\"1348\">Photodynamic Therapy (PDT)<\/strong><\/p><\/li><li class=\"\" data-start=\"1351\" data-end=\"1390\"><p class=\"\" data-start=\"1353\" data-end=\"1390\"><strong data-start=\"1353\" data-end=\"1388\">Sonophotodynamic Therapy (SPDT)<\/strong><\/p><\/li><li class=\"\" data-start=\"1391\" data-end=\"1426\"><p class=\"\" data-start=\"1393\" data-end=\"1426\"><strong data-start=\"1393\" data-end=\"1424\">Tumor Treating Fields (TTF)<\/strong><\/p><\/li><li class=\"\" data-start=\"1427\" data-end=\"1465\"><p class=\"\" data-start=\"1429\" data-end=\"1465\"><strong data-start=\"1429\" data-end=\"1463\">Gene Therapy (e.g., PTEN, p53)<\/strong><\/p><\/li><li class=\"\" data-start=\"1466\" data-end=\"1498\"><p class=\"\" data-start=\"1468\" data-end=\"1498\"><strong data-start=\"1468\" data-end=\"1496\">Maitake mushroom extract<\/strong><\/p><\/li><li class=\"\" data-start=\"1499\" data-end=\"1534\"><p class=\"\" data-start=\"1501\" data-end=\"1534\"><strong data-start=\"1501\" data-end=\"1532\">Coley Vaccine (Coley Fluid)<\/strong><\/p><\/li><li class=\"\" data-start=\"1535\" data-end=\"1574\"><p class=\"\" data-start=\"1537\" data-end=\"1574\"><strong data-start=\"1537\" data-end=\"1572\">High-dose intravenous Vitamin C<\/strong><\/p><\/li><li class=\"\" data-start=\"1575\" data-end=\"1608\"><p class=\"\" data-start=\"1577\" data-end=\"1608\"><strong data-start=\"1577\" data-end=\"1606\">Low-dose Naltrexone (LDN)<\/strong><\/p><\/li><li class=\"\" data-start=\"1609\" data-end=\"1634\"><p class=\"\" data-start=\"1611\" data-end=\"1634\"><strong data-start=\"1611\" data-end=\"1632\">Alpha-lipoic acid<\/strong><\/p><\/li><li class=\"\" data-start=\"1635\" data-end=\"1687\"><p class=\"\" data-start=\"1637\" data-end=\"1687\"><strong data-start=\"1637\" data-end=\"1685\">Whole-body or localized hyperthermia therapy<\/strong><\/p><\/li><li class=\"\" data-start=\"1688\" data-end=\"1771\"><p class=\"\" data-start=\"1690\" data-end=\"1771\"><strong data-start=\"1690\" data-end=\"1729\">Immunotherapies and cancer vaccines<\/strong>, including <strong data-start=\"1741\" data-end=\"1771\">autologous cancer vaccines<\/strong><\/p><\/li><\/ul><h3 class=\"\" data-start=\"1773\" data-end=\"1799\">Mechanisms of Action<\/h3><p class=\"\" data-start=\"1800\" data-end=\"2038\">New GcMAF exerts its therapeutic effect by activating macrophages to target abnormal cells, including cancer. It also demonstrates <strong data-start=\"1931\" data-end=\"1961\">anti-angiogenic properties<\/strong>, which may help inhibit the formation of new blood vessels that feed tumors.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bf35980 elementor-widget elementor-widget-menu-anchor\" data-id=\"bf35980\" data-element_type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div id=\"Flow\" class=\"elementor-menu-anchor\"><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-49f2500 elementor-widget elementor-widget-text-editor\" data-id=\"49f2500\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<h3><span style=\"text-decoration: underline\">Things To Avoid<\/span><\/h3>\n<p>Gc-MAF can be safely used with a wide variety of drugs and other treatments.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c3d371e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c3d371e\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-cf7969f\" data-id=\"cf7969f\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-acea05e elementor-widget elementor-widget-spacer\" data-id=\"acea05e\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-096aa1c elementor-widget elementor-widget-text-editor\" data-id=\"096aa1c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<h2 id=\"id01\">Treatment<\/h2><ul><li>Treatment is by intramuscular (IM) or subcutaneous (SC) injection of GcMAF macrophage activating factor, 3-7 times per week (or as prescribed by the treating medical doctor). See <strong><span class=\"see_below\">Dosing Recommendations<\/span><\/strong> below.<\/li><li>Treatment in our clinics has also been by intratumoral (IT) injection, although IM and SC injection is by far the most common means of administration.<\/li><li><strong><span style=\"color: #ff0000\">Good aseptic technique with ethanol is required when using the vials<\/span>.<\/strong><\/li><\/ul><h4><span style=\"text-decoration: underline\">Dosing Recommendations For Second Generation GcMAF<\/span><\/h4><ul><li><span style=\"color: var(--ast-global-color-2);font-family: Arial, Helvetica, Verdana, sans-serif;font-size: 0.933333rem;background-color: inherit\">The dosage and frequency of second-generation GcMAF administration should be determined by the treating physician and\/or the patient, based on individual health needs and response to treatment.<br data-start=\"327\" data-end=\"330\" \/>For further guidance, please contact us at <a class=\"\" href=\"https:\/\/saisei-mirai.or.jp\/en\/enq-eng\/\" target=\"_new\" rel=\"noopener\" data-start=\"373\" data-end=\"453\">https:\/\/saisei-mirai.or.jp\/en\/enq-eng\/<\/a>.\u00a0<\/span><\/li><\/ul>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-f5287d7 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"f5287d7\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-0f2f71f\" data-id=\"0f2f71f\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a15d88e elementor-widget elementor-widget-spacer\" data-id=\"a15d88e\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0e10230 elementor-widget elementor-widget-text-editor\" data-id=\"0e10230\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<h2 data-start=\"165\" data-end=\"230\"><strong data-start=\"165\" data-end=\"182\">GcMAF Immuno Therapy<\/strong><br data-start=\"182\" data-end=\"185\" \/><strong data-start=\"185\" data-end=\"230\">Access New GcMAF and Dietary MAF Products<\/strong><\/h2><p class=\"\" data-start=\"232\" data-end=\"492\">Patients and healthcare providers can obtain <strong data-start=\"277\" data-end=\"298\">New GcMAF therapy<\/strong> (injectable) developed by Saisei Mirai through our official <a href=\"https:\/\/saisei-mirai.jp\/\"><strong data-start=\"359\" data-end=\"387\">Saisei Mirai online shop<\/strong><\/a>.<br data-start=\"388\" data-end=\"391\" \/>For oral formulations, our <strong data-start=\"418\" data-end=\"440\">Dietary MAF series<\/strong> is available via the <a href=\"https:\/\/saisei-pharma.jp\/\"><strong data-start=\"462\" data-end=\"491\" data-is-only-node=\"\">Saisei Pharma online shop<\/strong><\/a>.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-cff72b3 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"cff72b3\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-ad83e44\" data-id=\"ad83e44\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-46b493d elementor-widget elementor-widget-text-editor\" data-id=\"46b493d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<h3><span style=\"text-decoration: underline\">High Dose GcMAF 2.5\u00a0ml multi-dose vials (1500\u00a0ng\/0.5\u00a0ml):<\/span><\/h3><ul><li style=\"list-style-type: none\"><ul><li><strong><span style=\"color: #ff0000\">Each multi-dose vial contains at least 4\u00a0doses GcMAF at 0.5\u00a0ml\/dose<\/span>.<\/strong> Vials are overfilled to 2.5\u00a0ml, so up to 5\u00a0doses GcMAF may be possible for each vial.<\/li><li><strong>Shipping and handling fee is from 18,000 JPY by FedEx.<\/strong><\/li><\/ul><\/li><\/ul><ul><li style=\"list-style-type: none\"><ul><li><strong><strong>Please keep the vials in the freezer. Only the vial you are using is kept in the fridge.<\/strong><\/strong><p>When frozen, it helps preserve activity for a very long time and prevents the settling of some solid parts in the GcMAF serum, which may start to occur with a few weeks to months of sitting in the fridge.<\/p><p>Stability tests indicate that 2nd Generation GcMAF is very temperature stable and retains maximum activity even after 4 weeks at room temperature and 1 week at 40 \u00b0C (104 \u00b0F). Shipping will not affect the activity of the product. Please refer to our Stability of GcMAF experiment report on our website for laboratory data.<\/p><\/li><\/ul><\/li><\/ul><ul><li style=\"list-style-type: none\"><ul><li>Please <span style=\"text-decoration: underline\"><a href=\"\/en\/enq-eng\/\">contact us<\/a><\/span> for pricing.<\/li><\/ul><\/li><\/ul><p><strong><strong>\u00a0<\/strong><\/strong><\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8affb8e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8affb8e\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-9cacbd7\" data-id=\"9cacbd7\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8eba751 elementor-widget elementor-widget-text-editor\" data-id=\"8eba751\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<h3><span style=\"text-decoration: underline\">Information<\/span><\/h3><p><b>If you wish to order Second\/Third Generation GcMAF Therapy made by Saisei Mirai, please visit our official <a href=\"https:\/\/www.saisei-mirai.jp\/\" target=\"_blank\" rel=\"noopener\">Saisei Mirai online shop<\/a>, or for oral MAF series products, our <a href=\"https:\/\/saisei-pharma.jp\/\" target=\"_blank\" rel=\"noopener\">Saisei Pharma online shop<\/a>.<\/b><\/p><ul><li>GcMAF is a natural immunotherapy product. Variation in GcMAF concentration is due to normal variation between blood samples. Just like Lymphocytes or Natural Killer cells vary in number between people and at any given time, so will the amount of Gc-MAF.<\/li><li>Charges for shipping and handling apply to each order. We use FedEx with tracking information. Each package includes cooling packs to keep GcMAF at a stable temperature during shipping. Our <span style=\"color: #ff0000\"><strong>Second Generation GcMAF<\/strong><\/span> is strong enough at room temperature to maintain a high level of activity for the days in transit. See more details about the <a href=\"https:\/\/www.saisei-mirai.or.jp\/gan\/pdf\/20120614-stability-of-gcmaf-in-serum.pdf\" target=\"_blank\" rel=\"noopener\">Stability of GcMAF in Serum<\/a> (PDF) report below for the tests done by the <a href=\"http:\/\/www.tokushima-u.ac.jp\/english\/department\/graduate_school\/technology.html\" target=\"_blank\" rel=\"noopener\">University of Tokushima<\/a> on stability by phagocytic activity of our GcMAF after short-term and long-term storage.<\/li><li>We ship Gc-MAF as a liquid in high quality multi-dose vials. After arrival the vials should be stored in the Freezer to maintain maximum activity until each injection.<\/li><\/ul>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-bf6b580 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"bf6b580\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-700285a\" data-id=\"700285a\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5dd47ee elementor-widget elementor-widget-text-editor\" data-id=\"5dd47ee\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<p class=\"\" data-start=\"148\" data-end=\"184\"><strong data-start=\"148\" data-end=\"184\">Estimated Stability of New GcMAF<\/strong><\/p><p class=\"\" data-start=\"186\" data-end=\"480\">New GcMAF retains its biological activity for a minimum of <strong data-start=\"245\" data-end=\"276\">2 weeks at room temperature<\/strong> and <strong data-start=\"281\" data-end=\"339\">at least 1 year under refrigerated conditions (2\u20138\u202f\u00b0C)<\/strong>.<br data-start=\"340\" data-end=\"343\" \/>Recent testing confirms that New GcMAF remains stable for <strong data-start=\"401\" data-end=\"438\">up to 4 weeks at room temperature<\/strong> without any significant loss of activity.<\/p><p class=\"\" data-start=\"482\" data-end=\"587\">However, for optimal preservation and long-term stability, we <strong data-start=\"544\" data-end=\"586\">recommend storing vials in the freezer<\/strong>.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-14ead05 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"14ead05\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-277f1fd\" data-id=\"277f1fd\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d5f8867 elementor-widget elementor-widget-text-editor\" data-id=\"d5f8867\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<p class=\"\" data-start=\"111\" data-end=\"143\"><strong data-start=\"111\" data-end=\"143\">Shipping Notes for New GcMAF<\/strong><\/p><p class=\"\" data-start=\"145\" data-end=\"423\">We use specialized packaging with ice packs to maintain stable temperatures during transit. New GcMAF is formulated to remain biologically active at room temperature for several days, making it robust enough to withstand typical shipping durations without compromising efficacy.<\/p><p class=\"\" data-start=\"425\" data-end=\"652\">All shipments contain <strong data-start=\"447\" data-end=\"479\">fresh, liquid-form New GcMAF<\/strong>, prepared just before dispatch to ensure optimal quality. Based on stability testing, the product is expected to arrive in <strong data-start=\"603\" data-end=\"651\">excellent condition with no loss of activity<\/strong>.<\/p><blockquote data-start=\"654\" data-end=\"729\"><p class=\"\" data-start=\"656\" data-end=\"729\">For more details, please refer to <a href=\"http:\/\/en\/macrophage_gcmaf_tests_eng\" data-wplink-url-error=\"true\" data-wplink-edit=\"true\"><strong data-start=\"690\" data-end=\"722\">Stability Tests of New GcMAF<\/strong><\/a> below.<\/p><\/blockquote>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7db857c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"7db857c\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-c4eb386\" data-id=\"c4eb386\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6b90215 elementor-widget elementor-widget-spacer\" data-id=\"6b90215\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f9e099f elementor-widget elementor-widget-text-editor\" data-id=\"f9e099f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<h2 id=\"id01\">Tests of Second Generation GcMAF<\/h2><p class=\"\" data-start=\"153\" data-end=\"199\"><strong data-start=\"153\" data-end=\"199\">Testing and Quality Assurance of New GcMAF<\/strong><\/p><p class=\"\" data-start=\"201\" data-end=\"264\">For full details, please visit our <a href=\"https:\/\/saisei-mirai.or.jp\/en\/macrophage_gcmaf_tests_eng\/\"><strong data-start=\"236\" data-end=\"258\">Tests of New GcMAF<\/strong><\/a> page.<\/p><p class=\"\" data-start=\"266\" data-end=\"581\">New GcMAF is produced in our state-of-the-art, sterile Cell Processing Center using a patented, enhanced method that yields a product <strong data-start=\"400\" data-end=\"433\">10\u201320 times more concentrated<\/strong> than conventional first-generation GcMAF. This advanced formulation offers <strong data-start=\"509\" data-end=\"552\">greater bioactivity, improved stability<\/strong>, and a high level of purity.<\/p><p class=\"\" data-start=\"583\" data-end=\"680\">To ensure the <strong data-start=\"597\" data-end=\"640\">highest standards of quality and safety<\/strong>, each batch undergoes rigorous testing:<\/p><ul data-start=\"682\" data-end=\"892\"><li class=\"\" data-start=\"682\" data-end=\"760\"><p class=\"\" data-start=\"684\" data-end=\"760\"><strong data-start=\"684\" data-end=\"706\">Sterile filtration<\/strong> using a 0.22-micron medical-grade filtration system<\/p><\/li><li class=\"\" data-start=\"761\" data-end=\"827\"><p class=\"\" data-start=\"763\" data-end=\"827\"><strong data-start=\"763\" data-end=\"784\">Endotoxin testing<\/strong> to confirm product safety before release<\/p><\/li><li class=\"\" data-start=\"828\" data-end=\"892\"><p class=\"\" data-start=\"830\" data-end=\"892\"><strong data-start=\"830\" data-end=\"849\">Activity assays<\/strong> to verify macrophage activation capability<\/p><\/li><\/ul><p class=\"\" data-start=\"894\" data-end=\"1002\">All procedures are performed under strict aseptic conditions to meet clinical-grade manufacturing standards.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b7cfeeb elementor-widget elementor-widget-text-editor\" data-id=\"b7cfeeb\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<h3><span style=\"text-decoration: underline\">Our Screening Process Includes the Following<\/span>:<\/h3><ul><li>TPHA test (Syphilis)<\/li><li>Hepatitis B surface antigen (HBsAg)<\/li><li>Hepatitis B core antibody (HBcAb)<\/li><li>Hepatitis B e antigen (HBeAg)<\/li><li>Hepatitis C virus (HCV)\u00a0antibody<\/li><li>HIV\u00a0antigen and antibody<\/li><li>Human T-cell lymphotropic virus (HTLV1) antibody<\/li><li>Endotoxins<\/li><\/ul>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-89a5ea8 elementor-widget elementor-widget-text-editor\" data-id=\"89a5ea8\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<h2 data-start=\"155\" data-end=\"186\"><strong data-start=\"155\" data-end=\"186\">Activity Tests of New GcMAF<\/strong>:<\/h2><p class=\"\" data-start=\"188\" data-end=\"386\">Activity testing of New GcMAF was conducted by researchers at the <strong data-start=\"254\" data-end=\"281\">University of Tokushima<\/strong>. The following results apply specifically to our <strong data-start=\"331\" data-end=\"344\">New GcMAF<\/strong> (formerly known as 2nd generation GcMAF).<\/p><h3 class=\"\" data-start=\"388\" data-end=\"426\">Stability Under Various Conditions<\/h3><ul data-start=\"428\" data-end=\"651\"><li class=\"\" data-start=\"428\" data-end=\"508\"><p class=\"\" data-start=\"430\" data-end=\"508\"><strong data-start=\"430\" data-end=\"473\">Room temperature (10\u201315\u202f\u00b0C) for 14 days<\/strong>: No significant loss of activity<\/p><\/li><li class=\"\" data-start=\"509\" data-end=\"585\"><p class=\"\" data-start=\"511\" data-end=\"585\"><strong data-start=\"511\" data-end=\"550\">High temperature (40\u202f\u00b0C) for 7 days<\/strong>: No significant loss of activity<\/p><\/li><li class=\"\" data-start=\"586\" data-end=\"651\"><p class=\"\" data-start=\"588\" data-end=\"651\"><strong data-start=\"588\" data-end=\"624\">Refrigerated (2\u20138\u202f\u00b0C) for 1 year<\/strong>: Activity remains stable<\/p><\/li><\/ul><h3 class=\"\" data-start=\"653\" data-end=\"676\">Summary of Findings<\/h3><p class=\"\" data-start=\"678\" data-end=\"863\">These tests confirm that <strong data-start=\"703\" data-end=\"745\">New GcMAF is highly temperature stable<\/strong>, maintaining full biological activity even under elevated temperatures for short periods. It remains effective after:<\/p><ul data-start=\"865\" data-end=\"1030\"><li class=\"\" data-start=\"865\" data-end=\"957\"><p class=\"\" data-start=\"867\" data-end=\"957\"><strong data-start=\"867\" data-end=\"908\">1\u20132 weeks at temperatures up to 40\u202f\u00b0C<\/strong>, making it suitable for <strong data-start=\"933\" data-end=\"955\">worldwide shipping<\/strong><\/p><\/li><li class=\"\" data-start=\"958\" data-end=\"1030\"><p class=\"\" data-start=\"960\" data-end=\"1030\"><strong data-start=\"960\" data-end=\"990\">1 year under refrigeration<\/strong>, with <strong data-start=\"997\" data-end=\"1030\">no measurable loss in potency<\/strong><\/p><\/li><\/ul><p class=\"\" data-start=\"1032\" data-end=\"1131\">For long-term storage, <strong data-start=\"1055\" data-end=\"1100\">we recommend keeping vials in the freezer<\/strong> to preserve optimal stability.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b590fd7 elementor-widget elementor-widget-spacer\" data-id=\"b590fd7\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cb33eed elementor-widget elementor-widget-text-editor\" data-id=\"cb33eed\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<h2 id=\"id01\">Research Papers and Presentations<\/h2><p>Please refer to our <span style=\"text-decoration: underline\"><a href=\"\/en\/reports\/\">research papers and presentations<\/a><\/span> page for detailed information.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-52557a9 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"52557a9\" data-element_type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-3650bea\" data-id=\"3650bea\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-311364c elementor-widget elementor-widget-image\" data-id=\"311364c\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"566\" height=\"743\" src=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/BIOMEDICINE.png\" class=\"attachment-large size-large wp-image-10974\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/BIOMEDICINE.png 566w, https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/BIOMEDICINE-229x300.png 229w\" sizes=\"(max-width: 566px) 100vw, 566px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-237136e elementor-widget elementor-widget-heading\" data-id=\"237136e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S075333222301692X?via%3Dihub\" target=\"_blank\">Adjunctive use of oral MAF is associated with no disease progression or mortality in hospitalized patients with Covid-19 pneumonia: the single-arm coral-maf1 prospective trial<\/a><\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-bc3a162\" data-id=\"bc3a162\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-bfee1bf elementor-widget elementor-widget-image\" data-id=\"bfee1bf\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"433\" height=\"85\" src=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/Research_square.png\" class=\"attachment-large size-large wp-image-10972\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/Research_square.png 433w, https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/Research_square-300x59.png 300w\" sizes=\"(max-width: 433px) 100vw, 433px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e4153ae elementor-widget elementor-widget-image\" data-id=\"e4153ae\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"556\" height=\"499\" src=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/names-list.png\" class=\"attachment-large size-large wp-image-10973\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/names-list.png 556w, https:\/\/saisei-mirai.or.jp\/en\/wp-content\/uploads\/sites\/3\/names-list-300x269.png 300w\" sizes=\"(max-width: 556px) 100vw, 556px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-353b1d0 elementor-widget elementor-widget-heading\" data-id=\"353b1d0\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/www.researchsquare.com\/article\/rs-2879067\/v1\" target=\"_blank\"><br>\n<br>\n\nEffect of degalactosylated bovine glycoprotein formulations MAF and M \u0441apsules on lymphopenia and clinical outcomes in hospitalized Covid-19 patients: a randomized clinical trial\n<\/a><\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"New GcMAFNEW GcMAF is produced using a patented process developed in Japan by Saisei Mirai, in collaboration w [&hellip;]","protected":false},"author":1,"featured_media":2452,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"site-sidebar-layout":"no-sidebar","site-content-layout":"default","ast-global-header-display":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_themeisle_gutenberg_block_has_review":false},"categories":[21],"tags":[],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/saisei-mirai.or.jp\/en\/wp-json\/wp\/v2\/posts\/2439"}],"collection":[{"href":"https:\/\/saisei-mirai.or.jp\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/saisei-mirai.or.jp\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/saisei-mirai.or.jp\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/saisei-mirai.or.jp\/en\/wp-json\/wp\/v2\/comments?post=2439"}],"version-history":[{"count":111,"href":"https:\/\/saisei-mirai.or.jp\/en\/wp-json\/wp\/v2\/posts\/2439\/revisions"}],"predecessor-version":[{"id":13216,"href":"https:\/\/saisei-mirai.or.jp\/en\/wp-json\/wp\/v2\/posts\/2439\/revisions\/13216"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/saisei-mirai.or.jp\/en\/wp-json\/wp\/v2\/media\/2452"}],"wp:attachment":[{"href":"https:\/\/saisei-mirai.or.jp\/en\/wp-json\/wp\/v2\/media?parent=2439"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/saisei-mirai.or.jp\/en\/wp-json\/wp\/v2\/categories?post=2439"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/saisei-mirai.or.jp\/en\/wp-json\/wp\/v2\/tags?post=2439"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}